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Research Scientist : Analytical Development – Autolus

The Autolus Ltd is looking for bright, enthusiastic Research Scientist to join a Process Development team committed to designing and characterising processes capable of producing high quality products for use in Autolus clinical trial programmes.

Position Requirements:

  • PhD or equivalent in Biology/Biochemistry or related
  • Familiarity with a number of analytical techniques (e.g. qPCR, ELISA, FACS, viral titre and p30, residual impurities, T-cell proliferation, exhaustion, cytokine release and killing assays)
  • Experience in assay development
  • Good understanding of cell biology and immunology
  • Experience in biopharmaceutical product characterisation/release desirable
  • Directly relevant biotechnology or pharmaceutical industry experience desirable
  • Understanding of and familiarity with regulatory guidance governing cell-based and biopharmaceutical development desirable
  • Flexible, self-motivated and focused on team outcomes
  • Strong verbal and written communication skills
Employer Autolus Ltd
Posted 03-12-2015
Location W12, London, United Kingdom
Discipline NA
Salary Competitive salary and benefits package, including a pension scheme, life assurance and private medical insurance
Official Notice

Responsibilities:

  • Characterise processing steps for yield, cell integrity and phenotype and clearance of impurities
  • Design and develop assays suitable to support product characterisation
  • Author development reports and regulatory documentation
  • Develop suitable product stability programmes
  • Assist in technology transfer to the Manufacturing group
  • Work with external service providers

Closing Date: 16-Dec-2015

Autolus is an exciting, ambitious and well-financed biotechnology company spun-out from University College London (UCL) to develop and commercialise the next generation of engineered T-cell therapies for haematological and solid tumours. They intend to be at the forefront of a revolution in medicine in which life- threatening diseases are treated with a patient’s own cells, modified outside the body and then returned to the patient where they will cure the disease. They are currently seeking bright, enthusiastic and motivated Scientists to work in their custom-built laboratories in West London. Successful candidates will join a rapidly-expanding, top-quality team and experience the excitement and sense of accomplishment presented by an innovative biotechnology start-up.

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