The Seattle Genetics are seeking a PhD scientist to participate in research projects involving the targeted delivery of anticancer drugs.
- The successful candidate should have a PhD degree in chemistry, biochemistry, or related disciplines, with additional postdoctoral experience.
- Research experience in organic and bioorganic chemistry, enzymology, and drug delivery is advantageous.
- The candidate must have a strong record of accomplishments as evidenced by key publications, sophisticated written and oral communication skills, and the desire to work in a fast-paced, flexible, collaborative team environment.
- The work will surround the delivery of conjugates to tumors, and the development of several novel technologies to improve intratumoral penetration, retention, and cellular uptake.
- Other work will also concern the impact that linker technologies have on drug delivery and retention.
- The work will involve the design of new ADCs, conjugation chemistry, purification and analytical technologies, and in vivo localization, biodistribution, therapy and toxicology studies
Seattle Genetics is a biotechnology company focused on developing and commercializing innovative, empowered antibody-based therapies for the treatment of cancer. We are the industry leader in antibody-drug conjugates (ADCs), a technology designed to harness the targeting ability of monoclonal antibodies to deliver cell-killing agents directly to cancer cells. ADCs are intended to spare non-targeted cells and thus reduce many of the toxic effects of traditional chemotherapy, while potentially enhancing antitumor activity.